Blurton S P, Raabe M, Greenlee M W, 2009, "fMRI correlates of saccadic adaptation" Perception 38 ECVP Abstract Supplement, page 120
fMRI correlates of saccadic adaptation
S P Blurton, M Raabe, M W Greenlee
Experimentally induced saccadic adaptation gradually changes saccadic gain as a consequence of intrasaccadic target displacements. We employed a double-step paradigm (McLaughlin, 1967 Perception & Psychophysics 2 359 - 362) for inward adaptation in an fMRI experiment and in-scanner oculomotor recording with twelve subjects. While the subjects performed a saccade to a peripheral target, this was displaced by 30% against the direction of gaze shift. In adaptation trials, the target step remained undetected and caused an average gain reduction of 18%. Activity during adaptation was contrasted against control trials with the same, but delayed target step. Our comparisons revealed two clusters located bilaterally in the posterior insular cortex to be significantly ( p corrected <0.05) less suppressed than during control trials. This region has been associated with the processing of vestibular signals (Eickhoff et al, 2006 Human Brain Mapping 27 611 - 621). A ROI analysis of cerebellar activation yielded significant effects related to saccadic adaptation, probably constituting motor learning processes. Our results suggest a lowering of perceptual threshold for vestibular information to guide the re-calibration of eye-head movements triggered by the post-saccadic error.
[Supported by German Federal BMBF (project 01GW0653).]
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